Avanafil Generic: What Is It and How It Works?

Avanafil was approved for the treatment of erectile dysfunction by the Food and Drug Administration (FDA) on April 27, 2012. It’s also known by the trademark names Stendra and Spedra.

Avanafil refers to the generic name of drug that is used in the treatment of erectile dysfunction (ED), and has been proven to be quite effective in treating it. It is safe and easy to use, but users should be aware of certain side effects that it may cause in rare cases, as well as knowing which medication to avoid if you choose to take Avanafil for your sexual performance needs. Please consult your doctor or health care physician if you have any questions about Avanafil, or to see if it is right for you.

Avanafil Generic: What Is It and How It Works?

What Is Avanafil Generic?

Avanafil Generic is the cheaper but also equally effective form of the brand name Stendra, used in treating erectile dysfunction. Avanafil works much in the same way as Stendra or Spedra (they share the same chemical structure), in which it contains the same PDE5 inhibitor as its main ingredients, allowing for a relaxation in blood vessels and improved blood flow into the penis. Manufactured in India, it is available for purchase in the United States and Europe.


Avanafil was approved for the treatment of erectile dysfunction by the Food and Drug Administration (FDA) on April 27, 2012 and by the European Medicines Agency (EMA) on June 21, 2013. Avanafil is also known by the trademark names Stendra and Spedra, and was developed by the pharmaceutical company Vivus Inc. In July 2013 Vivus announced their partnership with the Menarini Group, which commercialized and promoted Avanafil in over 40 European countries, as well as in Australia and New Zealand.

Avanafil FDA Approval

The FDA approved the use of Avanafil in 2012. Its status in the United States and Europe is legal, although you must obtain a prescription from your doctor or health care physician before receiving the drug. More information about Avanafil can be found at FDA website.

How Avanafil Works?

Initially intended as a treatment for treating high blood pressure and hypertension, Avanafil is used to treat erectile dysfunction. Avanafil relaxes muscles of the blood vessels and increases blood flow to certain areas of the body, namely the genitals, for a prolonged erection and thereby extending the duration of sexual activity.

After taking the Avanafil oral tablet, the drug will have a dissolution effect in the body, and within 30 minutes it will take effect, although in some trials, the effects of the drug started as little as 15 minutes after ingestion. Avanafil can be taken with or without food, although it is recommended to avoid taking it while eating high fatty foods.

Avanafil will not immediately cause an erection; sexual stimulation must occur for the increased blood flow to the genitals to take effect for the duration of action. Do not take more than one dose of of Avanafil in a span of 24 hours. This can lead to a prolonged erection, which can be damaging to the genitals and users may experience intense pain when erections last longer than four hours. Do not consume alcohol, as it can impede the effects of the drug.

Please be aware of the mechanism of action before taking this drug. For more information, please contact your health care provider or physician.

How Long Does It Last?

With various other erectile dysfunction alternatives on the market, each one has different effects on the body, and the half life varies from drug to drug. How long does it last? Take a look at the chart below to see how each drug compares:

Drug How Quickly It Works How Long Effects Last
Avanafil 15 to 30 minutes 6 hours
Cialis 15 to 45 minutes 36 hours
Levitra / Staxyn 25 minutes* 4 to 5 hours
Viagra 30 minutes* 4 to 5 hours

Where Can I Buy Avanafil?

Avanafil can be purchased at a variety of locations online and in person. Several websites offer Avanafil for sale, in both generic and brand name forms. The best method in obtaining Avanafil is to go to your local drug store or pharmacy to receive your prescription to ensure the highest quality and accountability. For users on the go, or those who do not have time to wait in long pharmacy lines, purchasing online is one option, but always be sure to check the legality of online transactions, and that the online vendor is to be trusted and verified.

Side Effects of Avanafil?

If you suffer from any sort of allergic reaction to taking Avanafil, no matter how mild or serious the symptoms might be, seek medical attention immediately. These symptoms may include difficulty or labored breathing, hives, swelling of the face, tongue, lips and/or throat. If you experience a sudden loss in vision, call a doctor or emergency services immediately. If you experience dizziness or nausea, or have any feelings of pain or numbness, or tingling in the neck, jaw, chest or arms, stop immediate use of Avanafil and call you doctor.

If you are having persistent problems, such as any listed below, stop taking Avanafil and seek medical attention from your doctor or health care physician:

  • any changes in vision or a sudden loss in vision;
  • ringing of the ears or a sudden loss in hearing;
  • symptoms relating to a heart attack, which may include chest pains or pain in the shoulder or jaw, sweating or nausea;
  • discomfort in one or both legs, which may have the feeling of swelling, pain, redness or warmth;
  • being short of breath, swelling in the feet or hands;
  • a feeling of lightheadedness or fainting;
  • erections that are painful or lasts for 4 hours or longer.

There are some common side effects known to occur when taking Avanafil. Please be aware of these before you consider to take the drug:

  • headache;
  • a flushing feeling, which may feel like a redness, warmth, or tingly sensation;
  • feelings of a cold virus such as stuffy or runny nose, pain in the back, sore throat.

What Other Drugs Will Affect Avanafil?

What is know about Avanafil is that it can affect users who are taking other medications in conjunction with Avanafil. Please be aware of any and all medication that could impact the body when taking both medications. Avoid taking any medications that are similar to Avanafil. This includes any other erectile dysfunction medication, as well as any medication that is used in the treatment of hypertension.

Inform your doctor about all the medication you may be using at a given time, and those you have started or stopped using while on treatment with Avanafil, which may include:

  • any other medications you may be using to treat erectile dysfunction;
  • any antibiotics;
  • anti-fungal medicine;
  • drugs use to treat high blood pressure or any prostate disorder;
  • medication to treat hepatitis C;
  • HIV and AIDS medication.

For a complete list of the above medications that may interact with using Avanafil, please consult your doctor.