Modafinil: Super Brain Boost or Bust?
Modafinil is an agent that promotes wakefulness, also known as a eugeroic. It’s currently used for treating conditions such as shift work sleep disorder, narcolepsy and the excessive daytime sleepiness often seen in people with obstructive sleep apnea. However, modafinil does have a popular off-brand use, namely to enhance cognitive performance and help people stay awake and be more alert.
From students who need to cram at the last minute to adults burning the candle at both ends, modafinil has become the agent of choice when it comes to staying awake, alert and intensely focused. It's become incredibly popular on college campuses, particularly with students in difficult majors, and among professionals in high-stress jobs.
Modafinil: a quick overview
The exact way modafinil works on the brain is currently unknown. It does block a molecule known as the dopamine transporter, an action shared by other stimulants, but not to a degree that explains why it works so well to increase wakefulness and cognition in people.
Modafinil has been proven to help people be more alert and boost cognitive ability in studies, including one out of the Ohio State University’s Department of Neurology in 2000. 72 patients with different degrees of multiple sclerosis were given a placebo with no effect and two different doses of modafinil over the course of nine weeks. The people who received the lower and higher doses of modafinil reported feeling much less fatigued than those given the placebo, although there was not much difference in the results between the high and low dose groups.
Even more impressively, the United States Air Force approved the use of modafinil for pilots on specific missions that required long periods of wakefulness and a high level of alertness. It has replaced the previously used stimulant Dexedrine, an amphetamine which proved to be undesirable to use in the field.
What you’ll find modafinil in
Modafinil is currently available under several brand names, including Provigil, Alertec, Modalert, Modapro, Modafil, Modvigil and Modatec. Names vary by region and manufacturer. There’s also Armodafinil, sold under the brand name Nuvigil, which is a specifically designed derivative of modafinil that contains what is believed to be its wakefulness agent.
Remember, generic Modafinil doesn’t mean ineffective
Generic version of Modafinil is simply the product without the branding and ad campaigns that drive up their cost. Millions of dollars go into the promotion and marketing of a new drug, and that expense is passed onto the consumer in the form of higher product prices. There may be some differences in appearance, tablet doses and sizes, and the inactive ingredients, but the same active medication component that is in the brand name is still in the generic version. The active medication is what makes the drug effective, not sits packaging, TV commercials or its physical appearance.
With generic modafinil, you’ll still receive the same benefits as you would with a name brand medicine, just at a fraction of the price. Like the popular branded names, generic drug compositions also receive approval by the Food and Drug Administration. So, whether you’re cost-conscious, on a budget, or simply don’t see the need to pay more just to get the brand name, the safe generic alternatives should work for you.
Modafinil online price: just $0.99 cents a tablet
With generic and other modafinil alternatives such as Modalert, you can pay prices as low as $0.99 cents per 200 mg tablet. The brand name Provigil runs much higher, averaging $10 to $20 per 200 mg pill in the United States and Canada.
Both medications feature high quality, pure modafinil, known to make you more alert and give you sharper focus. But with generic alternatives like Modalert by Sun Pharma, you’ll be able to save money and enjoy the boost without the drain on your wallet.
The FDA-approved brain boost
Modafinil is FDA-approved for treatment of certain sleep disorders in adults over 18. For a medication to receive FDA-approval, it must undergo rigorous testing for safety and effectiveness, as briefly outlined below.
• An application to the FDA is made only after at least three and a half years of laboratory testing.
• If the FDA gives the okay, the drug enters three testing phases that are designed to examine safety and effectiveness.
• Phase one involves 20 to 80 healthy volunteers taking the drug for about one year to check safety and establish a profile.
• In Phase two, 100 to 300 patients who volunteer take the drug for two years to test its effectiveness.
• During Phase three, 1,000 to 3,000 patients in medical settings take the drug and are carefully monitored for one to four years.
The company that developed the medicine must submit another application to the FDA if it passes all three phases, and that process takes another two and a half years. If the FDA approves the application, the drug becomes available to doctors to prescribe. Many drugs submitted to the FDA never make it out of the three phases and onto the pharmacy shelves.
A medication that has FDA-approval has undergone at least six years of testing prior to being available for doctors to give to their patients. Unlike some herbal stimulants, which don’t have to get approval from the FDA to be sold on the shelves or online, FDA-approved medications like modafinil have been thoroughly tested for effectiveness and safety with some independent oversight.
Even after the drug is on the market, the makers are still required to tell the FDA about any new findings, including side effects, reactions, and interactions. When you’re taking a drug approved by the FDA, you have a better idea of its safety and effectiveness than you do of supplements that don’t go through such a rigorous process.
Sun Pharma’s high-quality modafinil
Sun Pharma is the maker of Modalert, a generic version of Cephalon’s Provigil. A very respected, multinational pharmaceutical company, Sun Pharma is based in India and has over $150 billion dollars in revenue. Around two-thirds of this income is from the United States, thanks to its effective and low-cost generic alternatives.
A 200 mg Modalert tablet contains 200 milligrams of high purity modafinil. A Provigil pill of the same strength costs 10 to 20 times as much as Modalert, making Modalert a quality alternative that is affordable.
For those new and old to Modafinil
Some modafinil users have moved to the newer Armodafinil, but Modalert still remains a favorite among even experienced users and a strong brand for new users to start out with. With its quality ingredients, proven track record of effectiveness and relatively low cost when compared to the brand names out on the market today, Modalert is leading the pack when it comes to generic modafinil alternatives.
Dosing guidelines and recommendations
Generally, a 100 mg dose in the morning is all people need to get through the entire day, although some users may find they need an additional 100 mg dose later, during tasks or activities that require extended focus and concentration. The Modalert 200 mg tablet comes with a break line so you can split the pill into two 100 mg tablets to meet your dosing needs. Doses of up to 400 mg per day have been given in clinical studies, but researchers found no additional benefit above the 200 mg dose in those study participants.
Try the 100 mg dose first and go from there. It’s easy to misjudge your needs, especially with a new medicine, so starting off slow is the recommended way to go. Taking more modafinil than you need may increase the risk of side effects and will result in a waste of tablets, costing you money in the long run.
Comparing Modalert and Modvigil, two modafinil generics
Modalert is a high-quality modafinil generic manufactured by Sun Pharma, while Modvigial is a generic manufactured by HAB Pharma. Both cost significantly less than the brand name Provigil, but beyond that, it’s actually a little hard to do a straight comparison between the two.
Essentially, while Modalert is more popular than Modvigial, it comes down to how your body actually responds to the medications. Overall, Sun Pharma's manufacturing techniques are more modern and refined than HAB Pharma’s, which results in fewer “bad” batches. A bad batch isn’t harmful to you, but the medication produced isn't as effective. Some users have reported a less intense experience with Modvigial than they had while taking Modalert, so the better of the two for you will depend on your personal preferences and your body’s responses to each one.
Modalert comes in flexible, thin blister-packs that are made of aluminum. The packaging makes it easy for you to carry the tablets around in your purse, bag or even your pockets without having to worry about damaging or wasting any of them. If you are snapping a 200 mg tablet in half, simply put the other half back into the empty blister-pack spot or in a small pill container.
Modvigial is available in compact plastic blister-packs that protect the tablets from harm during travel. The plastic containers holding each pill in the blister-pack strips can be separated, leaving with you with small pods that hold one pill each. If you’re splitting 200 mg Modvigial into two 100 mg segments, you can put the remaining 100 mg half into the empty pod until you need it.
Both Modalert and Modvigial’s 200 mg tablets have break lines in the middle, so you can easily snap a tablet in half to create two 100 mg doses. This gives you control over the dosing, so you can take the tablets on your preferred schedule without having to waste medication.
Generic modafinil side effects
As with any medication, modafinil has side effects ranging from mild to serious. Stop taking modafinil if the side effects are intense or interfering with your life. Common side effects include:
• Pain in the back
• Runny or stuffy nose
• Upset stomach
• Problems going to sleep or staying asleep.
Speak to your doctor if you experience the above side effects and they become bothersome or persistent.
More serious but rare modafinil side effects and reactions have included serious skin disorders. Stop using modafinil immediately and consult a doctor if you experience a fever, rash or other sign of a skin issue.
Don’t drink after taking modafinil, as this can make the dizziness worse. It’s not known if this medicine is passed in breast milk, so speak to your doctor before taking modafinil if you’re pregnant or nursing. If you have a history of certain heart conditions or heart value problems, such as left ventricular hypertrophy, it’s not recommended you take modafinil.
Some medicines interact with modafinil. Ketoconazole, for instance, can increase modafinil’s side effects. Other medicines, such as phenobarbital, aren’t as effective if taken with modafinil, and modafinil can increase the likelihood of side effects from certain medications. Check the drug literature and speak with your physician if you’re unsure about the interactions between your other medicines and modafinil before you start taking it.
Can I become dependent on modafinil?
There’s naturally concerns about dependence and the potential of withdrawal symptoms when it comes to modafinil, as these were seen with some cognitive improvement drugs of the past such as Adderall and Ritalin. These fears have become more prevalent topics in the media, as countless college students and high-stress professionals sing modafinil’s praises and draw more attention to the drug.
The good news is that the dependence fears appear to be entirely premature. Modafinil isn’t an amphetamine and does not spike dopamine or norepinephrine in an unnatural way like Ritalin does, so it doesn’t have the common hallmarks seen with drugs that foster dependency. It is worth noting that if you’ve had problems with substance abuse in the past, any drug can pose a potential risk to you, so you may want to look into natural solutions instead.
Users have not reported any physical dangers after they stopped taking modafinil. The chief complaint among users who were no longer taking modafinil is the disappointment and frustration of returning to their previous levels of cognitive function. This “slowed down” sensation appears to fade for most people within a few days.
Will modafinil make me a genius?
Unfortunately, a tablet that makes you an instant genius like you may have seen in the movies hasn’t been invented yet. Modafinil is known as “smart drug” or “cognitive enhancer,” the basic idea of which is used in the popular 2011 Bradley Cooper movie “Limitless,” but its effects are not nearly as dramatic in real life as you see in the film.
With modafinil, you may experience improved memory, a sharper focus, feel more alert, and even have an improved mood, as some studies have shown it boosts dopamine brain levels. Users have also reported feeling less stressed, enjoying a stronger sense of motivation and having more drive in their daily lives.
While modafinil is not the magic pill that is the centerpiece of “Limitless,” it offers life-changing benefits for many of its users. With the affordable generic alternatives, such as Modalert, available on the market today, modafinil is certainly more than worth a try.
Modafinil testimonials: what real users are saying
‘I was extremely skeptical with ordering Modafinil online from India. I gave it shot because it's just too expensive in the US, even with insurance package. I have taken Provigil before and can attest that Modalert by Sun Pharma is the real deal. Go for it! Amazing product, ultra-fast delivery service. I'm your customer for life. Thanks!’