Dapoxetine: Definition, How Work and Used

Dapoxetine is a breakthrough potency compound which has been formulated specifically for the treatment of premature ejaculation (PE).

Dapoxetine is a revolutionary aid to end frustrating sexual health issues. Men can finally enjoy an outstanding sex life with the help of a tablet – millions of previously desperate men around the world now enjoy long-lasting, firmer erections.

You too can achieve long-lasting erections and excellent ejaculations with the aid of medical science.

What Is Dapoxetine?

Dapoxetine is a breakthrough potency compound which has been formulated specifically for the treatment of premature ejaculation (PE). Premature ejaculation is a surprisingly commonly encountered obstacle for sexually active men between the ages of 18 and 64 years. PE can strike men anywhere, at any time. Precision treatment of the ejaculatory response is now possible, and Dapoxetine has helped millions of men and their partners across the world to achieve a better sex life.

How Does Dapoxetine Work?

Scientists initially discovered and classified the compound as a selective serotonin re-uptake inhibitor (SSRI), due to be used as an antidepressant. However, they found that Dapoxetine has other exciting features.

The human male’s ejaculatory system is connected to the spinal cord and regulated by stimuli relayed as signals from the genitals to the brain stem. In short, ejaculation is controlled by the central nervous system. The central nervous system (the CNS) can be manipulated or influenced by the precise application of sophisticated drugs. How does it work?

The compound postpones ejaculation by inhibiting the body’s serotonin transporter. This leads to an increase in serotonin (the “feelgood hormone”) in a particular place and time in your body, which ensures a delay in ejaculation.

How Long Does It Last?

It is a top-selling potency enhancer that will really work and is popularly used to prolong sexual intercourse significantly. The active ingredient will keep your erection firm for many hours. Dapoxetine controls the nerve impulses generated during extreme sexual arousal and lets you engage in creative and long-lasting sex without premature climax.

Users report using Dapoxetine with Sildenafil (Viagra) or Tadalafil (Cialis) to achieve a firm erection and then making the most of the 12 hours of potency enhancement. Dapoxetine will allow you to control your erection and ejaculate for 12 hours after you take your tablet. There is no more reliable or easy way to achieve a prolonged and very satisfactory ejaculation.

Can Dapoxetine Make a Difference to My Sexual Potency?

Published scientific studies confirm that Dapoxetine (Priligy) is an effective treatment of PE. Also, different dosages can be tailored to treat different kinds of PE, and the active ingredient dosage can be adapted to address either lifelong PE or newly acquired PE. The fact remains that Dapoxetine provides clear-cut benefits and improves sexual control and enjoyment for men and their sexual partners.

Dapoxetine: Definition, How Work and Used

Mechanism of Action

The brain can be described as a sort of “circuit” which runs on a chemical called serotonin. Specific areas (receptors) in the brain are tasked with reabsorbing excess serotonin, but, in short: the more serotonin, the better and happier your brain functions. Therefore, SSRIs (Selective Serotonin Reuptake Inhibitors) are used to stop these specialized receptors from reabsorbing serotonin, thereby amplifying brain activity and influencing moods.

Dapoxetine’s mechanism of action is not clear, though the substance has been proven to inhibit the serotonin transporter. This causes an increase in available serotonin in the brain and heightens action at the post synaptic cleft causing a noticeable, measurable and repeatable ejaculatory delay.

What Makes Dapoxetine Different from Other SSRI’S?

Why not use any of the many SSRI’s on the market to achieve ejaculatory delay? The answer is that unlike other SSRIs, Dapoxetine is absorbed extremely rapidly and has a remarkably fast action. This means that it cannot be used as a ‘general’ antidepressant. Rather, the rapid action can be tailored to deliver a delay in ejaculatory response, while the fast elimination process ensures that the drug does not accumulate in the body to cause side effects.

Your doctor may give you a prescription for other SSRI’s as an off-label treatment for premature ejaculation. However, PE sufferers must then take a daily dosage of the medication to provide some efficacy, and there is an increased risk of drug accumulation in the body. These other SSRI’s are known to paradoxically also cause a decrease in sexual libido and may also cause erectile dysfunction.

Is Dapoxetine Legal in USA?

Eli Lilly originally created the SSRI called Dapoxetine, but as it was not an effective treatment for depression, further research stalled. They sold the patent to Johnson & Johnson in 2003 and subsequently to ALZA, who is currently pursuing FDA approval for Dapoxetine as a treatment for PE in the USA.

Dapoxetine is legal and widely used in more than 50 countries in Europe and across the world where it is marketed as Priligy, Westoxetin, and other brands or names. It is, however, still stalled in phase III clinical trials in the United States. The FDA has not yet approved Dapoxetine for the purpose of treatment of premature ejaculation and is therefore not legally available in the USA yet.

FDA Approval

As Dapoxetine is a proven treatment for PE and exhibits very few side effects, the owner of the brand confidently expects Federal Drug Administration approval soon. However, it can be obtained from reputable online pharmacies from around the world.

Recreational Use

Although the primary application is that of medical treatment for premature ejaculation, indications are that the product enjoys widespread recreational use. Reviews show that its popularity is due to its quick effect, duration of action, demonstrable results, economical price, and minor side effects.

Prospective users often ask: ‘how long does it last?’. The answer is a resounding: “Long enough, thanks!”

Where to Buy Dapoxetine without Prescription?

As top quality generic versions of Dapoxetine are manufactured in India under very strict quality controls, users can safely purchase a choice product from reputable online pharmacies.

Indian pharmaceutical companies can manufacture generic medications at a very low price. Quality generic drugs are identical to the original drug, but the prices are extremely competitive as Indian pharmaceutical companies need not abide by a patent that protects “original” medicinal products in the US and most other countries. A reputable online distributor can provide the ‘real thing,’ and is completely safe.

How to Use Dapoxetine

You can take your tablet around an hour up to three hours before you expect sexual activity. The Dapoxetine works for up to 12 hours, and the sex will last as long as you choose. Published clinical studies that Dapoxetine can delay the premature release of ejaculate by as long as four times! You can take your tab with or without food, and with almost no reduction in the rate of absorption even if you meal is higher in fat content.

Dapoxetine Dosages

It is recommended that you take your Dapoxetine with a full glass of water. The usual recommended starting dose is one 30 mg tablet, which you take 1 to 3 hours before anticipated sex. If the 30 mg dose is insufficient, you will achieve success when taking 60 mg of Dapoxetine for perfect control over your sexual encounter. Do not take a higher dosage than indicated or more than 1 tablet during 24 hours. As you only take a tablet before you have sex, you never have to be concerned about missed doses.

Side Effects of Dapoxetine

Unlike other SSRI’s, Dapoxetine offers high rates of sexual satisfaction with very mild side effects when used according to the instructions. A few users may experience:

  • nausea;
  • a dry mouth;
  • dizziness;
  • headache;
  • insomnia.

These side effects are usually fleeting and are very likely to disappear with regular product use.

Warnings and Precautions

Men who suffer from heart failure or another significant heart disease should avoid Dapoxetine, and men who receive antidepressant treatments such as other SSRIs, serotonin-norepinephrine re-uptake inhibitors, or tricyclic antidepressants should use the compound cautiously, only after consultation with a doctor. There are known contraindications in men with hepatic impairment and also in those receiving CYP3A4 inhibitors (e.g. ketoconazole, telithromycin and ritonavir).